Publications 2014

Y. T. Lau, E. Reading, G. L. Hura, K. L. Tsai, A. Laganowsky, F. J. Asturias, J. A. Trainer, C. V. Robinson and T. O. Yates
Structure of a designed protein cage that self-assembles into a highly porous cube.
Nat Chem 2014,6(12), 1065-1071

S. Mehmood, J. Marcoux, J. T. Hopper, T. M. Allison, I. Liko, A. J. Borysik and C. V. Robinson
Charge reduction stabilizes intact membrane protein complexes for mass spectrometry.
J Am Chem Soc 2014, 136(49), 17010-17012

J. T. Hopper and C. V. Robinson
Mass spectrometry quantifies protein interactions – from molecular chaperones to membrane porins.
Angew Chem Int Ed 2014, 53(51), 14002-14015

M. Zhou and C. V. Robinson
Flexible membrane proteins: functional dynamics captured by mass spectrometry.
Curr Opin Struct Biol 2014, 28, 122-130

C. Schmidt and C. V. Robinson
A comparative cross-linking strategy to probe conformational changes in protein complexes.
Nat Protoc2014, 9(9),2224-2236

M. Fairhead, G. Veggiani, M. Lever, J. Yan, D. Mesner, C. V. Robinson, O. Duschek, P. A. van der Merwe and M. Howarth
SpyAvidin hubs enable precise and ultrastable orthogonal nanoassembly.
J Am Chem Soc 2014, 136(35), 12355-12363

V. A. Mikhailov, T. H. Mize, J. L. Benesch and C. V. Robinson
Mass-selective soft-landing of protein assemblies with controlled landing energies.
Anal Chem2014, 86(16),8321-8328

A. Laganowsky, E. Reading, T. M. Allison, M. B. Ulmschneider, M. T. Degiacomi, A. J. Baldwin and C. V. Robinson
Membrane proteins bind lipids selectively to modulate their structure and function.
Nature 2014, 510(7503), 172-175

Y. Gordiyenko, C. Schmidt, M. D. Jennings, D. Matak-Vinkovic, G. D. Pavitt and C. V. Robinson
eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core.
Nat Commun 2014, 5, 3902

M. B. van Eldijk, B. J. Pieters, V. A. Mikhailov, C. V. Robinson, J. C. M. van Hest and J. Mecinovic
Catenane versus ring: do both asemblies of CS2 hydrolase exhibit the same stability and catalytic activity?
Chem Sci 2014, 5(7), 2879-2884

D. Hewitt, E. Marklund, D J. Scott, C. V. Robinson and A. J. Borysik
A hydrodynamic comparison of solution and gas phase proteins and their complexes.
J Phys Chem B 2014,118(29), 8489-8495

J. Wolf, E. Valkov, M. D Allen, B. Meineke, Y. Gordiyenko, S. H. McLaughlin, T. M. Olsen, C. V. Robinson, M. Bycroft, M. Stewart and L. A. Passmore
Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation.
EMBO J 2014, 33(14), 1514-1526

J. Marcoux, A. Politis, D. Rinehart, D. P. Marshall, M. I. Wallace, L. K. Tamm and C. V. Robinson
Mass spectrometry defines the C-terminal dimerisation domain and enables modeling of the structure of full-length OmpA.
Structure 2014, 22(5), 781-790

M. Zhou, A. Politis, R. B. Davies, I. Liko, K.–J. Wu, A. Stewart, D. Stock and C. V. Robinson
Ion mobility mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility.
Nat Chem 2014,6(3), 208-215

N. C. Wortham, M. Martinez, Y. Gordiyenko, C. V. Robinson and C. G. Proud
Analysis of the subunit organization of the elF2 complex reveals new insights into its structure and regulation.
FASEB J 2014, 28(5), 2225-37

I. Mathavan, S. Zirah, S. Mehmood, H. G. Choudhury, C. Goulard, Y. Li, C. V. Robinson, S. Rebuffat and K. Beis
Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides.
Nat Chem Biol 2014, 10(5),340-342

G. K. Hochberg, H. Ecroyd, C. Liu, D. Cox, D. Cascio, M. R. Sawaya, M. P. Collier, J. Stroud, J. A. Carver, A. J. Baldwin, C. V. Robinson, D. S. Eisenberg, J. L. Benesch and A. Laganowsky
The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc Natl Acad Sci USA 2014, 111(16), 1562-1570

E. Torreira, A. R. Seabra, H. Marriott, M. Zhou, O. Llorca, C. V. Robinson, H. G. Carvalho, C. Fernández-Tornero and P. J. Pereira
The structures of cytosolic and plastid-located glutamine synthetases from Medicago truncatula reveal a common and dynamic architecture.
Acta Crystallogr D Biol Crystallogr 2014, 70(4), 981-993

A. Politis, F. Stengel, Z. Hall, H. Hernández, A. Leitner, T. Walzthoeni, C. V. Robinson and R. Aebersold
A mass spectrometry-based hybrid method for structural modelling of protein complexes
Nature Methods 2014,11(4), 403-406

C. A. Ewens, S Panico, P. Kloppsteck, C. McKeown, I. O. Ebong, C. V. Robinson, X. Zhang and P. S. Freemont
The p97-FAF1 protein complex reveals a common mode of p97 adaptor binding.
J Biol Chem 2014, 289(17), 12077-12084

A. Politis, C. Schmidt, E. Tjioe, A Sali and C. V. Robinson
Determining the 3D topologies of heteromeric protein assemblies by a mass-spectrometry based hybrid approach.
Biophys J 2014, 106, 466A-466A

P. P. Mangione, R. Procari, J. D. Gillmore, G. W. Taylor, G. A. Tennent, P. N. Hawkins, S. P. Wood, M. B. Pepys, V. Bellotti, M. Porcari, S. Giorgetti, L. Marchese, S. Raymondi, M. Stoppini, P. Pucci, M. Monti, L. C. Serpell, W. Chen, A. Relini, J. Marcoux, C. V. Robinson and I. R. Clatworthy
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proc Natl Acad Sci USA 2014, 111(4), 1539-1544

N. Zhang, E. Lawton, M. Buck, Y. Gordiyenko, C. V. Robinson and N. Joly
Subunit dynamics and nucleotide-dependent asymmetry of an AAA transcription complex.
J Mol Biol 2014, 426(1), 71-83

C. Schmidt and C. V. Robinson
Dynamic protein ligand interactions – insights from mass spectrometry.
FEBS J 2014, 281(8), 1950-1964.

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