Publications 2018

H-Y Yen, K. K. Hoi, I. Liko, G. Hedger, M. R. Horrell, W. Song, D. Wu, P. Heine,  T. Warne, Y. Lee, B. Carpenter, A. Plückthun, C. G. Tate, M. S. P. Sansom and C. V. Robinson
PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling.
Nature, 2018, 559(7714): 423-427 doi.org/10.1038/s41586-018-0325-6

L. Kuhlen, P. Abrusci, S. Johnson, J. Gault, J. Deme, J. Caesar, T. Dietsche, M. T. Mebrhatu, T. Ganief, B. Macek, S. Wagner, C. V. Robinson and S. M. Lea
Structure of the core of the type three secretion system export apparatus.
Nat Struct Mol Biol, 2018, 25: 583–590  doi.org/10.1038/s41594-018-0086-9

M. Romano, G. Fusco, H. G. Choudhury, S. Mehmood, C. V. Robinson, S. Zirah, J. D. Hegemann, E. Lescop, M. A. Marahiel, S. Rebuffat, A. de Simone and K. Beis
Structural basis for natural product selection and export by bacterial ABC transporters.
ACS Chem Biol, 2018 13(6): 1598-1609 doi: 10.1021/acschembio.8b00226

K. Gupta, J. Li, I. Liko, J. Gault, C. Bechara, D. Wu, J. T. S. Hopper, K. Giles, J. L. P. Benesch and C. V. Robinson.
Identifying key membrane protein lipid interactions using mass spectrometry.
Nat Protoc, 2018, (5): 1106-1120 doi: 10.1038/nprot.2018.014   

Y. Liu, G. D. Gupta, D. D. Barnabas, F. G. Agircan, S. Mehmood, D. Wu, E. Coyaud, C. M. Johnson, S. H. McLaughlin, A. Andreeva, S. M. V. Freund, C. V. Robinson, S. W. T. Cheung, B. Raught, L. Pelletier and M. van Breugel.
Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 2018, 9(1): 1731 doi: 10.1038/s41467-018-04122-x

J. R. O. Eaton, Y. Alenazi, K. Singh, G. Davies, L. Geis-Asteggiante, B. Kessler, C. V. Robinson, A. Kawamura and S. Bhattacharya
The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins.
J Biol Chem, 2018,  293: 6134-6146 doi: 10.1074/jbc.RA117.000487

S. Zoll, H. Lane-Serff, S. Mehmood, J. Schneider, C. V. Robinson, M. Carrington and M. K. Higgins.
The structure of serum resistance-associated protein and its implications for human African trypanosomiasis.
Nat Microbiol, 2018, 3: 295–301 doi:10.1038/s41564-017-0085-3

M. Wojnowska, J. Gault, S. C. Yong, C. V. Robinson and B. C. Berks
Precursor–Receptor Interactions in the Twin Arginine Protein Transport Pathway Probed with a New Receptor Complex Preparation.
Biochemistry, 2018, 57(10): 1663–1671 doi: 10.1021/acs.biochem.8b00026

E. Natan, T. Endoh, L. Haim-Vilmovsky, T. Flock, G. Chalancon, J. T. S. Hopper, B. Kintses, P. Horvath, L. Daruka, G. Fekete, C. Pál, B. Papp, E. Oszi, Z. Magyar, J. A. Marsh, A. H. Elcock, M.  Babu, C. V. Robinson, N. Sugimoto & S. A. Teichmann
Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins.
Nat Struct Mol Biol, 2018, 25: 279–288 doi:10.1038/s41594-018-0029-5

J. R. Bolla, J. B. Sauer, D. Wu, S. Mehmood, T. M. Allison and C. V. Robinson
Direct observation of the influence of cardiolipin and antibiotics on lipid II binding to MurJ
Nat Chem, 2018, 10, 363–371  doi:10.1038/nchem.2919

 


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