Our team comprises researchers with diverse backgrounds: from chemists and physicists to structural biologists and engineers, we all work towards the common goal of deciphering protein structure and function in the gas phase.
Congratulations to Francesco Fiorentino
At the 22nd IMSC 2018 Conference held in Florence in August, Francesco won a poster award sponsored by “Chemistry, A European Journal” and Wiley for one of the six best posters in the conference (among ~1100 posters). See the poster here.
July 2018: Carol was honoured and delighted to take over the role of President 2018-2020 for the Royal Society of Chemistry.
National Academy of Sciences
May 2017: Carol has been elected to the National Academy of Sciences US as a foreign associate in recognition of her significant contributions to science. She would like to thank her research group over the years for all their efforts which have contributed to this honour. NAS Group Celebration
Forthcoming Lectures 2018:
25th September: Cambridge Institute for Medical Research (CIMR) 20th Anniversary Symposium, Cambridge, UK - 'Membrane Proteins - the Lipid Connection'
30th September: HUPO World Congress 2018, Orlando, USA - 'Understanding Critical Protein Lipid Interactions'
PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling.
H-Y Yen, K. K. Hoi, I. Liko, G. Hedger, M. R. Horrell, W. Song, D. Wu, P. Heine, T. Warne, Y. Lee, B. Carpenter, A. Plückthun, C. G. Tate, M. S. P. Sansom and C. V. Robinson
Nature, 2018, 559(7714): 423–427
Ligand binding to a G protein-coupled receptor captured in a mass spectrometer.
H. Y. Yen, J. T. S. Hopper, I. Liko, T. M. Allison, Y. Zhu, D. Wang, M. Stegmann, S. Mohammed, B. Wu and C. V. Robinson.
Sci Adv, 2017, 3(6): e1701016
The role of interfacial lipids in stabilizing membrane protein oligomers.
K. Gupta, J. A. Donlan, J. T. Hopper, P. Uzdavinys, M. Landreh, W. B.Struwe, D. Drew, A. J. Baldwin, P.J. Stansfeld, C.V. Robinson.
Nature, 2017, 541: 421-424
High-resolution mass spectrometry of small molecules bound to membrane proteins.
J. Gault, J. A. C. Donlan, I. Liko, J. T. Hopper, K. Gupta, N. G. Housden, W. B. Struwe, M. T. Marty, T. Mize, C. Bechara, Y. Zhu, W. Beilil, C. Kleanthous, M. Belov, E. Damoc, A. Makarov and C. V. Robinson
Nat Methods, 2016, 13(4): 333-336
Membrane proteins bind lipids selectively to modulate their structure and function.
A. Laganowsky, E. Reading, T. M. Allison, M. B. Ulmschneider, M. T. Degiacomi, A. J. Baldwin and C. V. Robinson
Nature 2014, 510(7503), 172-175